Description
A selective small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) studied in preclinical models involving NAD+ salvage, adipocyte metabolism, lipogenesis, skeletal-muscle regeneration, and
related cellular pathways. Premium Research Peptide.
Compound Information
Technical specifications
Molecular Profile
What Is 5-Amino-1MQ?
Full Name5-Amino-1-methylquinolinium
TypeSmall-molecule NNMT inhibitor
Compound ClassQuinolinium derivative
Free Cation FormulaC10H11N2+
Free Cation Weight159.21 g/mol
Iodide Salt FormulaC10H11IN2
Iodide Salt Weight286.11 g/mol
Research TargetNNMT
Storage Requirements
Stability Information
Sources & References
Peer-reviewed research and scientific resources
Journal of Medicinal Chemistry
Structure-Activity Relationship for Small-Molecule Inhibitors of Nicotinamide N-Methyltransferase
Biochemical Pharmacology
Selective and Membrane-Permeable Small-Molecule Inhibitors of Nicotinamide N-Methyltransferase Reverse High-Fat-Diet-Induced Obesity in Mice
Biochemical Pharmacology
Small-Molecule Nicotinamide N-Methyltransferase Inhibitor Activates Senescent Muscle Stem Cells and Improves Regenerative Capacity of Aged Skeletal Muscle
Scientific Reports
Combined Nicotinamide N-Methyltransferase Inhibition and Reduced-Calorie Diet Normalizes Body Composition and Enhances Metabolic Benefits in Obese Mice
Journal of Pharmaceutical and Biomedical Analysis
Bioanalytical and Pharmacokinetic Research Involving 5-Amino-1-Methylquinolinium
Journal of Obstetrics and Gynaecology Research
Small-Molecule Inhibition of Nicotinamide N-Methyltransferase Shows Antiproliferative Activity in HeLa Cells
Scientific Reports
Reduced-Calorie Diet and NNMT Inhibition in Diet-Induced Obesity Models
Diabetes, Obesity and Metabolism
NNMT Inhibition in Obesity-Related Metabolic Dysfunction
Additional information
| Dosage | 10MG |
|---|
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