NAD+

$65.00

Description

An endogenous dinucleotide coenzyme studied in cellular energy metabolism, redox reactions, DNA-repair pathways, enzymatic signaling, and NAD+-dependent cellular processes. Premium Research Compound.

Compound Information

Chemical and structural properties


Molecular Profile

NAD+ Structure

Essential dinucleotide coenzyme

Coenzyme
Endogenous
CAS Number
53-84-9
Molecular Formula

C21H27N7O14P2
Molecular Weight
663.43 g/mol
Type
Dinucleotide coenzyme
Oxidation State
Oxidized form
Components
Nicotinamide and adenine nucleotides



PubChem Database


Biological Targets

Enzyme Interactions

Cofactor and cosubstrate for multiple enzyme families

Sirtuins
NAD+-dependent deacylases
PARPs
ADP-ribosyltransferases
CD38
NAD+ glycohydrolase
Oxidoreductases
Redox-reaction enzymes
Primary Role
Electron transfer and signaling


Physical Properties

Handling & Storage

Stability and storage requirements

Appearance
White to off-white powder
Solubility
Water soluble
Dry Compound
-20°C, protected from light
Moisture
Store desiccated
Prepared Solution
Refrigerate and use promptly

Sources & References

Peer-reviewed research and scientific resources

Trends in Cell Biology

NAD+ and Sirtuins in Aging and Disease

2014

Review

DOI: 10.1016/j.tcb.2014.04.002

PMID: 24786309

Imai S, Guarente L


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Circulation

NAD+ Metabolism in Cardiac Health, Aging, and Disease

2021

Review

DOI: 10.1161/CIRCULATIONAHA.121.056589

PMID: 34843394

Abdellatif M, Sedej S, Kroemer G


View Source


Circulation Research

Sirtuins and NAD+ in the Development and Treatment of Metabolic
and Cardiovascular Diseases

2018

Review

DOI: 10.1161/CIRCRESAHA.118.312498

PMID: 30355082

Kane AE, Sinclair DA


View Source


Nature Metabolism

NAD+ Homeostasis in Health and Disease

2020

Review

DOI: 10.1038/s42255-019-0161-5

PMID: 32694684

Katsyuba E, Romani M, Hofer D, Auwerx J


View Source


Additional information

Dosage

500MG

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